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==Crystal structure of the ABC transporter in the cobalt transport system==
==Crystal structure of the ABC transporter in the cobalt transport system==
<StructureSection load='2yz2' size='340' side='right' caption='[[2yz2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2yz2' size='340' side='right'caption='[[2yz2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2yz2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YZ2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2yz2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YZ2 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yz2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yz2 RCSB], [http://www.ebi.ac.uk/pdbsum/2yz2 PDBsum], [http://www.topsan.org/Proteins/RSGI/2yz2 TOPSAN]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yz2 OCA], [https://pdbe.org/2yz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yz2 RCSB], [https://www.ebi.ac.uk/pdbsum/2yz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yz2 ProSAT], [https://www.topsan.org/Proteins/RSGI/2yz2 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ECFA2_THEMA ECFA2_THEMA] ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (Probable). Expression of the complex plus RibU in E.coli allows riboflavin uptake; uptake does not occur in the absence of RibU or the EcfA1A2T complex.<ref>PMID:23359690</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/2yz2_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/2yz2_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yz2 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Thermotoga maritima]]
[[Category: Large Structures]]
[[Category: Bessho, Y.]]
[[Category: Thermotoga maritima MSB8]]
[[Category: Ethayathullah, A S.]]
[[Category: Bessho Y]]
[[Category: Kaur, P.]]
[[Category: Ethayathullah AS]]
[[Category: Padmanabhan, B.]]
[[Category: Kaur P]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Padmanabhan B]]
[[Category: Singh, T P.]]
[[Category: Singh TP]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama S]]
[[Category: Abc transporter]]
[[Category: Atp-binding protein]]
[[Category: Cobalt transport]]
[[Category: Hydrolase]]
[[Category: Inner membrane]]
[[Category: Membrane]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nucleotide-binding]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Tm0222]]
Retrieved from "https://proteopedia.org/2yz2"