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==IgE Fv SPE7 complexed with a recombinant thioredoxin==
==IgE Fv SPE7 complexed with a recombinant thioredoxin==
<StructureSection load='1oaz' size='340' side='right' caption='[[1oaz]], [[Resolution|resolution]] 2.78&Aring;' scene=''>
<StructureSection load='1oaz' size='340' side='right'caption='[[1oaz]], [[Resolution|resolution]] 2.78&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1oaz]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OAZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OAZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1oaz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OAZ FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1f6m|1f6m]], [[1keb|1keb]], [[1m7t|1m7t]], [[1srx|1srx]], [[1t7p|1t7p]], [[1tho|1tho]], [[1txx|1txx]], [[1xoa|1xoa]], [[1xob|1xob]], [[2tir|2tir]], [[2trx|2trx]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.78&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oaz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1oaz RCSB], [http://www.ebi.ac.uk/pdbsum/1oaz PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oaz OCA], [https://pdbe.org/1oaz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oaz RCSB], [https://www.ebi.ac.uk/pdbsum/1oaz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oaz ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oa/1oaz_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oa/1oaz_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oaz ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1oaz" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Thioredoxin|Thioredoxin]]
*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: James, L C.]]
[[Category: James LC]]
[[Category: Roversi, P.]]
[[Category: Roversi P]]
[[Category: Tawfik, D.]]
[[Category: Tawfik D]]
[[Category: Allergy]]
[[Category: Antibody]]
[[Category: Antibody-complex]]
[[Category: Conformational diversity]]
[[Category: Electron transport]]
[[Category: Ige]]
[[Category: Immune system]]
[[Category: Multispecficity]]
[[Category: Redox-active center]]

Latest revision as of 08:06, 4 March 2026

IgE Fv SPE7 complexed with a recombinant thioredoxin

1oaz, resolution 2.78Å

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