1j3d: Difference between revisions
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==Solution structure of the C-terminal domain of the HMGB2== | |||
<StructureSection load='1j3d' size='340' side='right'caption='[[1j3d]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1j3d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J3D FirstGlance]. <br> | |||
| | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3d OCA], [https://pdbe.org/1j3d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j3d RCSB], [https://www.ebi.ac.uk/pdbsum/1j3d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j3d ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HMGB2_PIG HMGB2_PIG] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j3/1j3d_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j3d ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[High mobility group protein|High mobility group protein]] | |||
__TOC__ | |||
== | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: | |||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
[[Category: Kurita | [[Category: Kurita J]] | ||
[[Category: Shimahara | [[Category: Shimahara H]] | ||
[[Category: Tate | [[Category: Tate S]] | ||
[[Category: Yoshida | [[Category: Yoshida M]] | ||
Latest revision as of 23:41, 27 December 2023
Solution structure of the C-terminal domain of the HMGB2
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