4q1h: Difference between revisions

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'''Unreleased structure'''


The entry 4q1h is ON HOLD  until Paper Publication
==Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching==
 
<StructureSection load='4q1h' size='340' side='right'caption='[[4q1h]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
Authors: Nair, A.V., Race, P.R., Till, M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4q1h]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q1H FirstGlance]. <br>
Description: Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide -branching
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q1h OCA], [https://pdbe.org/4q1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q1h RCSB], [https://www.ebi.ac.uk/pdbsum/4q1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q1h ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PKSI_BACSU PKSI_BACSU] Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. May have a role in the decarboxylation of the (S)-3-methylglutaryl group attached to PksL.<ref>PMID:16757561</ref> <ref>PMID:17234808</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Large Structures]]
[[Category: Nair AV]]
[[Category: Race PR]]
[[Category: Till M]]