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[[Image:1jex.jpg|left|200px]]


{{Structure
==SOLUTION STRUCTURE OF A67V MUTANT OF RAT FERRO CYTOCHROME B5==
|PDB= 1jex |SIZE=350|CAPTION= <scene name='initialview01'>1jex</scene>
<StructureSection load='1jex' size='340' side='right'caption='[[1jex]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
<table><tr><td colspan='2'>[[1jex]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JEX FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR,  models</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jex OCA], [https://pdbe.org/1jex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jex RCSB], [https://www.ebi.ac.uk/pdbsum/1jex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jex ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CYB5_RAT CYB5_RAT] Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. It is also involved in several steps of the sterol biosynthesis pathway, particularly in the C-6 double bond introduction during the C-6 desaturation.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/1jex_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jex ConSurf].
<div style="clear:both"></div>


'''SOLUTION STRUCTURE OF A67V MUTANT OF RAT FERRO CYTOCHROME B5'''
==See Also==
 
*[[Cytochrome b5 3D structures|Cytochrome b5 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1JEX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JEX OCA].
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Blankman JI]]
[[Category: Blankman, J I.]]
[[Category: Dangi B]]
[[Category: Dangi, B.]]
[[Category: Guiles RD]]
[[Category: Guiles, R D.]]
[[Category: Shahzad N]]
[[Category: Shahzad, N.]]
[[Category: HEM]]
[[Category: cytochrome b5]]
[[Category: electron transport]]
[[Category: solution structure]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:02:36 2008''