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==Crystal structure of the Thermus thermophilus 70S ribosome in complex with amicoumacin, mRNA and three deacylated tRNAs in the A, P and E sites==
#REDIRECT [[4w2f]] This PDB entry is obsolete and replaced by 4w2f
<StructureSection load='4rb7' size='340' side='right' caption='[[4rb7]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4rb7]] is a 25 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RB7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RB7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=UAM:AMICOUMACIN+A'>UAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=4SU:4-THIOURIDINE-5-MONOPHOSPHATE'>4SU</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=7MG:7N-METHYL-8-HYDROGUANOSINE-5-MONOPHOSPHATE'>7MG</scene>, <scene name='pdbligand=MIA:2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5-MONOPHOSPHATE'>MIA</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rb5|4rb5]], [[4rb6|4rb6]], [[4rb8|4rb8]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rb7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rb7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rb7 RCSB], [http://www.ebi.ac.uk/pdbsum/4rb7 PDBsum]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Thermus thermophilus]]
[[Category: Bogdanov, A A.]]
[[Category: Bulkley, D.]]
[[Category: Dontsova, O A.]]
[[Category: Efimenko, T A.]]
[[Category: Efremenkova, O V.]]
[[Category: Konevega, A L.]]
[[Category: Kusochek, P.]]
[[Category: Malanicheva, I A.]]
[[Category: Mankin, A S.]]
[[Category: Osterman, I A.]]
[[Category: Polikanov, Y S.]]
[[Category: Rodnina, M V.]]
[[Category: Serebryakova, M V.]]
[[Category: Sergiev, P V.]]
[[Category: Shaw, K J.]]
[[Category: Steitz, T A.]]
[[Category: Szal, T.]]
[[Category: Tashlitsky, V N.]]
[[Category: 30s subunit with amicoumacin]]
[[Category: 50s subunit of the 2nd 70s ribosome in the asu]]
[[Category: 70s ribosome]]
[[Category: Amicoumacin]]
[[Category: And e-site trnas of the 2nd 70s ribosome in the asu]]
[[Category: Antibiotic]]
[[Category: Deacylated a-]]
[[Category: Functional complex of bacterial 70s ribosome with antibiotic amicoumacin]]
[[Category: Inhibition of translation]]
[[Category: Mrna]]
[[Category: P-]]
[[Category: Ribosome-antibiotic complex]]
[[Category: Translocation inhibitor]]

Latest revision as of 15:51, 10 December 2014

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