2xx8: Difference between revisions
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== | |||
<StructureSection load='2xx8' size='340' side='right' caption='[[2xx8]], [[Resolution|resolution]] 1.55Å' scene=''> | ==Crystal structure of N,N-dimethyl-4-(3-(trifluoromethyl)-4,5,6,7- tetrahydro-1H-indazol-1-yl)benzamide in complex with the ligand binding domain of the Rat GluA2 receptor and glutamate at 2.2A resolution.== | ||
<StructureSection load='2xx8' size='340' side='right'caption='[[2xx8]], [[Resolution|resolution]] 1.55Å' scene=''> | |||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xx8]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2xx8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XX8 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1NE:N,N-DIMETHYL-4-[3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]BENZAMIDE'>1NE</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1NE:N,N-DIMETHYL-4-[3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]BENZAMIDE'>1NE</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xx8 OCA], [https://pdbe.org/2xx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xx8 RCSB], [https://www.ebi.ac.uk/pdbsum/2xx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xx8 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2xx8" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
*[[ | *[[Glutamate receptor 3D structures|Glutamate receptor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Aldegheri | [[Category: Aldegheri L]] | ||
[[Category: Austin | [[Category: Austin NE]] | ||
[[Category: Ballantine | [[Category: Ballantine S]] | ||
[[Category: Ballini | [[Category: Ballini E]] | ||
[[Category: Bax | [[Category: Bax BD]] | ||
[[Category: Bradley | [[Category: Bradley DM]] | ||
[[Category: Clarke | [[Category: Clarke BP]] | ||
[[Category: | [[Category: DalNegro G]] | ||
[[Category: Harries | [[Category: Harries M]] | ||
[[Category: Harris | [[Category: Harris AJ]] | ||
[[Category: Harrison | [[Category: Harrison SA]] | ||
[[Category: Melarange | [[Category: Melarange RA]] | ||
[[Category: Mookherjee | [[Category: Mookherjee C]] | ||
[[Category: Mosley | [[Category: Mosley J]] | ||
[[Category: Oliosi | [[Category: Oliosi B]] | ||
[[Category: Smith | [[Category: Smith KJ]] | ||
[[Category: Thewlis | [[Category: Thewlis KM]] | ||
[[Category: Ward | [[Category: Ward SE]] | ||
[[Category: Woollard | [[Category: Woollard PM]] | ||
[[Category: Yusaf | [[Category: Yusaf SP]] | ||
Latest revision as of 01:31, 21 November 2024
Crystal structure of N,N-dimethyl-4-(3-(trifluoromethyl)-4,5,6,7- tetrahydro-1H-indazol-1-yl)benzamide in complex with the ligand binding domain of the Rat GluA2 receptor and glutamate at 2.2A resolution.
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