4pk5: Difference between revisions
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==Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with Amg-1== | ==Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with Amg-1== | ||
<StructureSection load='4pk5' size='340' side='right' caption='[[4pk5]], [[Resolution|resolution]] 2.79Å' scene=''> | <StructureSection load='4pk5' size='340' side='right'caption='[[4pk5]], [[Resolution|resolution]] 2.79Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4pk5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PK5 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4pk5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PK5 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PKJ:N-(1,3-BENZODIOXOL-5-YL)-2-{[5-(4-METHYLPHENYL)[1,3]THIAZOLO[2,3-C][1,2,4]TRIAZOL-3-YL]SULFANYL}ACETAMIDE'>PKJ</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.79Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PKJ:N-(1,3-BENZODIOXOL-5-YL)-2-{[5-(4-METHYLPHENYL)[1,3]THIAZOLO[2,3-C][1,2,4]TRIAZOL-3-YL]SULFANYL}ACETAMIDE'>PKJ</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pk5 OCA], [https://pdbe.org/4pk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pk5 RCSB], [https://www.ebi.ac.uk/pdbsum/4pk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pk5 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/I23O1_HUMAN I23O1_HUMAN] Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.<ref>PMID:17671174</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 16: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4pk5" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Dioxygenase 3D structures|Dioxygenase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Ishii T]] | ||
[[Category: | [[Category: Kohno T]] | ||
[[Category: | [[Category: Tojo S]] | ||
Latest revision as of 03:25, 21 November 2024
Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with Amg-1
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