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==THE CRYSTAL STRUCTURE OF LEISHMANIA MAJOR DUTPASE IN COMPLEX DUMP==
 
<StructureSection load='2yaz' size='340' side='right' caption='[[2yaz]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
==The Crystal Structure of Leishmania major dUTPase in complex dUMP==
<StructureSection load='2yaz' size='340' side='right'caption='[[2yaz]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2yaz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YAZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YAZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2yaz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YAZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yay|2yay]], [[2yb0|2yb0]], [[2cje|2cje]], [[2cic|2cic]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yaz OCA], [https://pdbe.org/2yaz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yaz RCSB], [https://www.ebi.ac.uk/pdbsum/2yaz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yaz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yaz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yaz RCSB], [http://www.ebi.ac.uk/pdbsum/2yaz PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O15826_LEIMA O15826_LEIMA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2yaz" style="background-color:#fffaf0;"></div>
==See Also==
*[[DUTPase 3D structures|DUTPase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Leishmania major]]
[[Category: Leishmania major]]
[[Category: DUTP diphosphatase]]
[[Category: Bosch-Navarrete C]]
[[Category: Bosch-Navarrete, C.]]
[[Category: Fogg MJ]]
[[Category: Fogg, M J.]]
[[Category: Gonzalez-Pacanowska D]]
[[Category: Gonzalez-Pacanowska, D.]]
[[Category: Hemsworth GR]]
[[Category: Hemsworth, G R.]]
[[Category: Moroz OV]]
[[Category: Moroz, O V.]]
[[Category: Scott B]]
[[Category: Scott, B.]]
[[Category: Wilson KS]]
[[Category: Wilson, K S.]]
[[Category: Hydrolase]]
[[Category: Leishmaniasis]]
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