4d4m: Difference between revisions

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'''Unreleased structure'''


The entry 4d4m is ON HOLD
==human PFKFB3 in complex with a pyrrolopyrimidone compound==
 
<StructureSection load='4d4m' size='340' side='right'caption='[[4d4m]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
Authors: Stgallay, S.A., Bennett, N., Critchlow, S., Davies, G., Debreczeni, J.E., Evans, N., Holdgate, G., Jones, N.P., Leach, L., Maman, S., McLoughlin, S., Preston, M., Rigoreau, L., Thomas, A., Walker, G., Walsch, J., Ward, R.A., Wheatley, E., Winter, J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4d4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D4M FirstGlance]. <br>
Description: human PFKFB3 in complex with a pyrrolopyrimidone compound
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.32&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BKV:7-(4-BROMOPHENYL)-5-PHENYL-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-ONE'>BKV</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d4m OCA], [https://pdbe.org/4d4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d4m RCSB], [https://www.ebi.ac.uk/pdbsum/4d4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d4m ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN] Synthesis and degradation of fructose 2,6-bisphosphate.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bennett N]]
[[Category: Critchlow S]]
[[Category: Davies G]]
[[Category: Debreczeni JE]]
[[Category: Evans N]]
[[Category: Holdgate G]]
[[Category: Jones NP]]
[[Category: Leach L]]
[[Category: Maman S]]
[[Category: McLoughlin S]]
[[Category: Preston M]]
[[Category: Rigoreau L]]
[[Category: Stgallay SA]]
[[Category: Thomas A]]
[[Category: Walker G]]
[[Category: Walsch J]]
[[Category: Ward RA]]
[[Category: Wheatley E]]
[[Category: Winter J]]

Latest revision as of 11:17, 9 May 2024

human PFKFB3 in complex with a pyrrolopyrimidone compound

4d4m, resolution 2.32Å

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