4rp3: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry 4rp3 is ON HOLD~~

==Crystal Structure of the L27 Domain of Discs Large 1 (target ID NYSGRC-010766) from Drosophila melanogaster bound to a potassium ion (space group P212121)==

~~Authors: Ghosh, A., Ramagopal, U., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4rp3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RP3 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=4RP3 FirstGlance].

~~Description:~~ Crystal Structure of the L27 Domain of Discs Large 1 (target ID NYSGRC-010766) from Drosophila melanogaster bound to a potassium ion (space group P212121)

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.36Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=4rp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rp3 OCA], [https://pdbe.org/4rp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rp3 RCSB], [https://www.ebi.ac.uk/pdbsum/4rp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rp3 ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/DLG1_DROME DLG1_DROME] During embryonic development, some isoforms are essential for proper neuronal differentiation and organization. Required for cell polarity; maintenance of apicobasal polarity. Plays a critical role at septate junctions in cellular growth control during larval development. The presence of a guanylate kinase domain suggests involvement in cellular adhesion as well as signal transduction to control cellular proliferation.<ref>PMID:10884224</ref> <ref>PMID:12657668</ref> <ref>PMID:1651169</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Drosophila melanogaster]]

[[Category: Large Structures]]

[[Category: Almo SC]]

[[Category: Ghosh A]]

[[Category: Ramagopal U]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4rp3 is ON HOLD
+==Crystal Structure of the L27 Domain of Discs Large 1 (target ID NYSGRC-010766) from Drosophila melanogaster bound to a potassium ion (space group P212121)==
+<StructureSection load='4rp3' size='340' side='right'caption='[[4rp3]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
-Authors: Ghosh, A., Ramagopal, U., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4rp3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RP3 FirstGlance]. <br>
-Description: Crystal Structure of the L27 Domain of Discs Large 1 (target ID NYSGRC-010766) from Drosophila melanogaster bound to a potassium ion (space group P212121)
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.36&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rp3 OCA], [https://pdbe.org/4rp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rp3 RCSB], [https://www.ebi.ac.uk/pdbsum/4rp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rp3 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DLG1_DROME DLG1_DROME] During embryonic development, some isoforms are essential for proper neuronal differentiation and organization. Required for cell polarity; maintenance of apicobasal polarity. Plays a critical role at septate junctions in cellular growth control during larval development. The presence of a guanylate kinase domain suggests involvement in cellular adhesion as well as signal transduction to control cellular proliferation.<ref>PMID:10884224</ref> <ref>PMID:12657668</ref> <ref>PMID:1651169</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Drosophila melanogaster]]
+[[Category: Large Structures]]
+[[Category: Almo SC]]
+[[Category: Ghosh A]]
+[[Category: Ramagopal U]]