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==Zinc Uptake Regulator Complexed With Zinc AND DNA==
==Zinc Uptake Regulator Complexed With Zinc AND DNA==
<StructureSection load='4mtd' size='340' side='right' caption='[[4mtd]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4mtd' size='340' side='right'caption='[[4mtd]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4mtd]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MTD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MTD FirstGlance]. <br>
<table><tr><td colspan='2'>[[4mtd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MTD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MTD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mte|4mte]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mtd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mtd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mtd RCSB], [http://www.ebi.ac.uk/pdbsum/4mtd PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mtd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mtd OCA], [https://pdbe.org/4mtd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mtd RCSB], [https://www.ebi.ac.uk/pdbsum/4mtd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mtd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ZUR_ECOLI ZUR_ECOLI] Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Gilston, B A.]]
[[Category: Escherichia coli K-12]]
[[Category: Halloran, T V.O.]]
[[Category: Large Structures]]
[[Category: Mondragon, A.]]
[[Category: Gilston BA]]
[[Category: Dna binding]]
[[Category: Mondragon A]]
[[Category: Dna binding protein-dna complex]]
[[Category: O'Halloran TV]]
[[Category: Dna-binding regulatory protein]]
[[Category: Helix-turn-helix]]
[[Category: Protein-dna complex]]
[[Category: Winged helix]]
[[Category: Winged-helix]]
[[Category: Zinc regulated repressor]]