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==Crystal Structure of uncharacterized conserved archael protein from Methanopyrus kandleri==
==Crystal Structure of uncharacterized conserved archael protein from Methanopyrus kandleri==
<StructureSection load='2iec' size='340' side='right' caption='[[2iec]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
<StructureSection load='2iec' size='340' side='right'caption='[[2iec]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2iec]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanopyrus_kandleri Methanopyrus kandleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IEC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2iec]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanopyrus_kandleri Methanopyrus kandleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IEC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2i52|2i52]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Q8TX89_METKA, MK0786 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2320 Methanopyrus kandleri])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iec OCA], [https://pdbe.org/2iec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iec RCSB], [https://www.ebi.ac.uk/pdbsum/2iec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iec ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2iec TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iec OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iec RCSB], [http://www.ebi.ac.uk/pdbsum/2iec PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2iec TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MPTD_METKA MPTD_METKA] Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).[HAMAP-Rule:MF_02130]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/2iec_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/2iec_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iec ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanopyrus kandleri]]
[[Category: Methanopyrus kandleri]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Bain, K T]]
[[Category: Bain KT]]
[[Category: Bonanno, J B]]
[[Category: Bonanno JB]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Dickey, M]]
[[Category: Dickey M]]
[[Category: Structural genomic]]
[[Category: Ozyurt S]]
[[Category: Ozyurt, S]]
[[Category: Powell A]]
[[Category: Powell, A]]
[[Category: Ramagopal UA]]
[[Category: Ramagopal, U A]]
[[Category: Sauder JM]]
[[Category: Sauder, J M]]
[[Category: Wasserman S]]
[[Category: Wasserman, S]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Tetramer with intra-molecular and inter-molecular disufide bond]]
[[Category: Unknown function]]

Latest revision as of 10:10, 30 August 2023

Crystal Structure of uncharacterized conserved archael protein from Methanopyrus kandleri

2iec, resolution 2.33Å

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