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==Crystal structure of the human small CTD phosphatase 3 isoform 1==
==Crystal structure of the human small CTD phosphatase 3 isoform 1==
<StructureSection load='2hhl' size='340' side='right' caption='[[2hhl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2hhl' size='340' side='right'caption='[[2hhl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2hhl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HHL FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HHL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HHL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KEG:12-TUNGSTOPHOSPHATE'>KEG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ta0|1ta0]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KEG:12-TUNGSTOPHOSPHATE'>KEG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTDSPL, C3orf8, NIF1, NIFL, YA22 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hhl OCA], [https://pdbe.org/2hhl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hhl RCSB], [https://www.ebi.ac.uk/pdbsum/2hhl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hhl ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2hhl TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hhl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hhl RCSB], [http://www.ebi.ac.uk/pdbsum/2hhl PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2hhl TOPSAN]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hh/2hhl_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hh/2hhl_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hhl ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2hhl" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Adams, J M]]
[[Category: Adams JM]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Atwell, S]]
[[Category: Atwell S]]
[[Category: Bain, K T]]
[[Category: Bain KT]]
[[Category: Boice, A]]
[[Category: Boice A]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Dickey, M]]
[[Category: Dickey M]]
[[Category: Emtage, S]]
[[Category: Emtage S]]
[[Category: Gheyi, T]]
[[Category: Gheyi T]]
[[Category: Groshong, C]]
[[Category: Groshong C]]
[[Category: Malashkevich, V N]]
[[Category: Malashkevich VN]]
[[Category: Structural genomic]]
[[Category: Ozyurt S]]
[[Category: Ozyurt, S]]
[[Category: Powell A]]
[[Category: Powell, A]]
[[Category: Ramagopal U]]
[[Category: Ramagopal, U]]
[[Category: Reyes C]]
[[Category: Reyes, C]]
[[Category: Rooney I]]
[[Category: Rooney, I]]
[[Category: Rutter ME]]
[[Category: Rutter, M E]]
[[Category: Sauder JM]]
[[Category: Sauder, J M]]
[[Category: Schwinn KD]]
[[Category: Schwinn, K D]]
[[Category: Thompson DA]]
[[Category: Thompson, D A]]
[[Category: Toro R]]
[[Category: Toro, R]]
[[Category: Wasserman SR]]
[[Category: Wasserman, S R]]
[[Category: Ctd phosphatase]]
[[Category: Hydrolase]]
[[Category: Keggins anion]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]

Latest revision as of 08:11, 13 August 2026

Crystal structure of the human small CTD phosphatase 3 isoform 1

2hhl, resolution 2.10Å

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