1kn5: Difference between revisions

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[[Image:1kn5.gif|left|200px]]


{{Structure
==SOLUTION STRUCTURE OF ARID DOMAIN OF ADR6 FROM SACCHAROMYCES CEREVISIAE==
|PDB= 1kn5 |SIZE=350|CAPTION= <scene name='initialview01'>1kn5</scene>
<StructureSection load='1kn5' size='340' side='right'caption='[[1kn5]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1kn5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KN5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KN5 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= adr6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kn5 OCA], [https://pdbe.org/1kn5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kn5 RCSB], [https://www.ebi.ac.uk/pdbsum/1kn5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kn5 ProSAT]</span></td></tr>
}}
</table>
 
== Function ==
'''SOLUTION STRUCTURE OF ARID DOMAIN OF ADR6 FROM SACCHAROMYCES CEREVISIAE'''
[https://www.uniprot.org/uniprot/SWI1_YEAST SWI1_YEAST] Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
1KN5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KN5 OCA].  
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kn/1kn5_consurf.spt"</scriptWhenChecked>
==Reference==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
1H, 13C and 15N resonance assignments and secondary structure of ADR6 DNA-binding domain., Tu X, Wu J, Xu Y, Shi Y, J Biomol NMR. 2001 Oct;21(2):187-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11727987 11727987]
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kn5 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Shi Y]]
[[Category: Shi, Y.]]
[[Category: Tu X]]
[[Category: Tu, X.]]
[[Category: Wu J]]
[[Category: Wu, J.]]
[[Category: Xu Y]]
[[Category: Xu, Y.]]
[[Category: adr6]]
[[Category: arid domain]]
[[Category: dna-binding]]
 
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