2v38: Difference between revisions

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[[Image:2v38.gif|left|200px]]<br />
<applet load="2v38" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2v38, resolution 1.50&Aring;" />
'''FAMILY 5 ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS IN COMPLEX WITH CELLOBIO-DERIVED NOEUROMYCIN'''<br />


==About this Structure==
==Family 5 endoglucanase Cel5A from Bacillus agaradhaerens in complex with cellobio-derived noeuromycin==
2V38 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]] with IDR, SO4, IFL and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Cellulase Cellulase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2V38 OCA]].  
<StructureSection load='2v38' size='340' side='right'caption='[[2v38]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
[[Category: Bacillus agaradhaerens]]
== Structural highlights ==
[[Category: Cellulase]]
<table><tr><td colspan='2'>[[2v38]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salipaludibacillus_agaradhaerens Salipaludibacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V38 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V38 FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
[[Category: Davies, G.J.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IDR:L-IDURONIC+ACID'>IDR</scene>, <scene name='pdbligand=IFL:(3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE'>IFL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Gloster, T.M.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v38 OCA], [https://pdbe.org/2v38 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v38 RCSB], [https://www.ebi.ac.uk/pdbsum/2v38 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v38 ProSAT]</span></td></tr>
[[Category: Meloncelli, P.J.]]
</table>
[[Category: Money, V.A.]]
== Function ==
[[Category: Stick, R.V.]]
[https://www.uniprot.org/uniprot/GUN5_SALAG GUN5_SALAG]  
[[Category: Tarling, C.A.]]
== Evolutionary Conservation ==
[[Category: Withers, S.G.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: GOL]]
Check<jmol>
[[Category: IDR]]
  <jmolCheckbox>
[[Category: IFL]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/2v38_consurf.spt"</scriptWhenChecked>
[[Category: SO4]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: carbohydrate metabolism]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: cellulose degradation]]
  </jmolCheckbox>
[[Category: endoglucanase]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v38 ConSurf].
[[Category: family 5]]
<div style="clear:both"></div>
[[Category: glycosidase]]
[[Category: glycoside hydrolase]]
[[Category: hydrolase]]
[[Category: noeuromycin]]
[[Category: polysaccharide degradation]]


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 17:42:55 2007''
==See Also==
*[[Glucanase 3D structures|Glucanase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salipaludibacillus agaradhaerens]]
[[Category: Davies GJ]]
[[Category: Gloster TM]]
[[Category: Meloncelli PJ]]
[[Category: Money VA]]
[[Category: Stick RV]]
[[Category: Tarling CA]]
[[Category: Withers SG]]

Latest revision as of 15:04, 13 December 2023

Family 5 endoglucanase Cel5A from Bacillus agaradhaerens in complex with cellobio-derived noeuromycin

2v38, resolution 1.50Å

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