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==Crystal Structure of Yeast NADH Kinase complexed with NADH==
==Crystal Structure of Yeast NADH Kinase complexed with NADH==
<StructureSection load='3afo' size='340' side='right' caption='[[3afo]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3afo' size='340' side='right'caption='[[3afo]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3afo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AFO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AFO FirstGlance]. <br>
<table><tr><td colspan='2'>[[3afo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AFO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AFO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POS5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NADH_kinase NADH kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.86 2.7.1.86] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3afo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3afo OCA], [https://pdbe.org/3afo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3afo RCSB], [https://www.ebi.ac.uk/pdbsum/3afo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3afo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3afo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3afo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3afo RCSB], [http://www.ebi.ac.uk/pdbsum/3afo PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/POS5_YEAST POS5_YEAST] Phosphorylates both NADH and NAD(+), with a twofold preference for NADH. Anti-oxidant factor and key source of the cellular reductant NADPH.<ref>PMID:12727869</ref> <ref>PMID:12912900</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: NADH kinase]]
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Ando, T]]
[[Category: Ando T]]
[[Category: Kawai, S]]
[[Category: Kawai S]]
[[Category: Mikami, B]]
[[Category: Mikami B]]
[[Category: Miyagi, H]]
[[Category: Miyagi H]]
[[Category: Murata, K]]
[[Category: Murata K]]
[[Category: Ochiai, A]]
[[Category: Ochiai A]]
[[Category: Ohashi, K]]
[[Category: Ohashi K]]
[[Category: Alpha/beta+beta sandwich]]
[[Category: Atp-binding]]
[[Category: Kinase]]
[[Category: Mitochondrion]]
[[Category: Nad]]
[[Category: Nadp]]
[[Category: Nucleotide-binding]]
[[Category: Transferase]]
[[Category: Transit peptide]]