4x08: Difference between revisions
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New page: '''Unreleased structure''' The entry 4x08 is ON HOLD Authors: Blanco, J. A., Garcia, J. M., Salazar, V. A., Sanchez, D., Moussauoi, M. Description: Structure of H128N/ECP mutant in com... |
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==Structure of H128N/ECP mutant in complex with sulphate anions at 1.34 Angstroms.== | |||
<StructureSection load='4x08' size='340' side='right'caption='[[4x08]], [[Resolution|resolution]] 1.34Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4x08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X08 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.34Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x08 OCA], [https://pdbe.org/4x08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x08 RCSB], [https://www.ebi.ac.uk/pdbsum/4x08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x08 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ECP_HUMAN ECP_HUMAN] Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.<ref>PMID:2501794</ref> <ref>PMID:19450231</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Blanco JA]] | |||
[[Category: Boix E]] | |||
[[Category: Garcia JM]] | |||
[[Category: Moussauoi M]] | |||
[[Category: Salazar VA]] | |||
[[Category: Sanchez D]] | |||
