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[[Image:1lvw.gif|left|200px]]


{{Structure
==Crystal structure of glucose-1-phosphate thymidylyltransferase, RmlA, complex with dTDP==
|PDB= 1lvw |SIZE=350|CAPTION= <scene name='initialview01'>1lvw</scene>, resolution 1.7&Aring;
<StructureSection load='1lvw' size='340' side='right'caption='[[1lvw]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TYD:THYMIDINE-5'-+DIPHOSPHATE'>TYD</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
<table><tr><td colspan='2'>[[1lvw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LVW FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Glucose-1-phosphate_thymidylyltransferase Glucose-1-phosphate thymidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.24 2.7.7.24]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
|GENE= RMLA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=145262 Methanothermobacter thermautotrophicus])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TYD:THYMIDINE-5-DIPHOSPHATE'>TYD</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lvw OCA], [https://pdbe.org/1lvw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lvw RCSB], [https://www.ebi.ac.uk/pdbsum/1lvw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lvw ProSAT], [https://www.topsan.org/Proteins/NESGC/1lvw TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O27819_METTH O27819_METTH]  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lvw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lvw ConSurf].
<div style="clear:both"></div>


'''Crystal structure of glucose-1-phosphate thymidylyltransferase, RmlA, complex with dTDP'''
==See Also==
 
*[[Glucose-1-phosphate thymidylyltransferase 3D structures|Glucose-1-phosphate thymidylyltransferase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1LVW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LVW OCA].
[[Category: Large Structures]]
[[Category: Glucose-1-phosphate thymidylyltransferase]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Single protein]]
[[Category: Christendat D]]
[[Category: Christendat, D.]]
[[Category: Dong A]]
[[Category: Dong, A.]]
[[Category: Pai EF]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Pai, E F.]]
[[Category: CL]]
[[Category: GOL]]
[[Category: SO4]]
[[Category: TYD]]
[[Category: nesg]]
[[Category: northeast structural genomics consortium]]
[[Category: nucleotide binding fold]]
[[Category: protein nucleotide complex]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:35:47 2008''

Latest revision as of 07:36, 14 February 2024

Crystal structure of glucose-1-phosphate thymidylyltransferase, RmlA, complex with dTDP

1lvw, resolution 1.70Å

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