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==The Crystal Structure of a Bacterial Regulatory Protein in the tetR Family from Rhodococcus RHA1 to 2.2A==
==The Crystal Structure of a Bacterial Regulatory Protein in the tetR Family from Rhodococcus RHA1 to 2.2A==
<StructureSection load='3him' size='340' side='right' caption='[[3him]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3him' size='340' side='right'caption='[[3him]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3him]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_jostii Rhodococcus jostii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HIM FirstGlance]. <br>
<table><tr><td colspan='2'>[[3him]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_jostii Rhodococcus jostii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HIM FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3him FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3him OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3him RCSB], [http://www.ebi.ac.uk/pdbsum/3him PDBsum], [http://www.topsan.org/Proteins/MCSG/3him TOPSAN]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3him FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3him OCA], [https://pdbe.org/3him PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3him RCSB], [https://www.ebi.ac.uk/pdbsum/3him PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3him ProSAT], [https://www.topsan.org/Proteins/MCSG/3him TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q0SD48_RHOJR Q0SD48_RHOJR]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/3him_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/3him_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3him ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Rhodococcus jostii]]
[[Category: Rhodococcus jostii]]
[[Category: Binkowski, T A]]
[[Category: Binkowski TA]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Evdokimova, E]]
[[Category: Evdokimova E]]
[[Category: Joachimiak, A]]
[[Category: Joachimiak A]]
[[Category: Kagan, O]]
[[Category: Kagan O]]
[[Category: Structural genomic]]
[[Category: Savchenko A]]
[[Category: Savchenko, A]]
[[Category: Stein AJ]]
[[Category: Stein, A J]]
[[Category: Bacterial]]
[[Category: Dna-binding]]
[[Category: Mcsg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Rha1]]
[[Category: Rhodococcus]]
[[Category: Tetr]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulator]]

Latest revision as of 10:00, 21 February 2024

The Crystal Structure of a Bacterial Regulatory Protein in the tetR Family from Rhodococcus RHA1 to 2.2A

3him, resolution 2.20Å

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