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==T. maritima RNase H2 in complex with nucleic acid substrate and calcium ions==
==T. maritima RNase H2 in complex with nucleic acid substrate and calcium ions==
<StructureSection load='3o3g' size='340' side='right' caption='[[3o3g]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='3o3g' size='340' side='right'caption='[[3o3g]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3o3g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O3G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O3G FirstGlance]. <br>
<table><tr><td colspan='2'>[[3o3g]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O3G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O3G FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2etj|2etj]], [[3o3f|3o3f]], [[3o3h|3o3h]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rnhB, TM_0915 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o3g OCA], [https://pdbe.org/3o3g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o3g RCSB], [https://www.ebi.ac.uk/pdbsum/3o3g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o3g ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o3g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o3g RCSB], [http://www.ebi.ac.uk/pdbsum/3o3g PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNH2_THEMA RNH2_THEMA] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3o3g" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
*[[User:Jaime.Prilusky/Test/tree|User:Jaime.Prilusky/Test/tree]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ribonuclease H]]
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Cerritelli, S M]]
[[Category: Cerritelli SM]]
[[Category: Chon, H]]
[[Category: Chon H]]
[[Category: Crouch, R J]]
[[Category: Crouch RJ]]
[[Category: Klimek, P]]
[[Category: Klimek P]]
[[Category: Nowotny, M]]
[[Category: Nowotny M]]
[[Category: Rychlik, M P]]
[[Category: Rychlik MP]]
[[Category: Hydrolase-dna-rna hybrid complex]]
[[Category: Nuclease]]
[[Category: Rnase h fold]]

Latest revision as of 09:27, 6 September 2023

T. maritima RNase H2 in complex with nucleic acid substrate and calcium ions

3o3g, resolution 2.10Å

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