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==Crystal structure of Staphylococcus aureus nucleoside diphosphate kinase complexed with UDP==
==Crystal structure of Staphylococcus aureus nucleoside diphosphate kinase complexed with UDP==
<StructureSection load='3q8v' size='340' side='right' caption='[[3q8v]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3q8v' size='340' side='right'caption='[[3q8v]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3q8v]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus Staphylococcus aureus subsp. aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q8V FirstGlance]. <br>
<table><tr><td colspan='2'>[[3q8v]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q8V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q8V FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q83|3q83]], [[3q86|3q86]], [[3q89|3q89]], [[3q8u|3q8u]], [[3q8y|3q8y]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ndk, SACOL1509 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46170 Staphylococcus aureus subsp. aureus])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q8v OCA], [https://pdbe.org/3q8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q8v RCSB], [https://www.ebi.ac.uk/pdbsum/3q8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q8v ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase Nucleoside-diphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q8v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q8v RCSB], [http://www.ebi.ac.uk/pdbsum/3q8v PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NDK_STAAC NDK_STAAC] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3q8v" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Nucleoside diphosphate kinase|Nucleoside diphosphate kinase]]
*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Nucleoside-diphosphate kinase]]
[[Category: Large Structures]]
[[Category: Staphylococcus aureus subsp. aureus]]
[[Category: Staphylococcus aureus subsp. aureus COL]]
[[Category: Gopal, B]]
[[Category: Gopal B]]
[[Category: Rajasree, K]]
[[Category: Rajasree K]]
[[Category: Srivastava, S K]]
[[Category: Srivastava SK]]
[[Category: A gamma phosphate]]
[[Category: Alpha-beta protein family]]
[[Category: Ferridoxin fold]]
[[Category: Magnesium]]
[[Category: Metal binding]]
[[Category: Nucleoside diphosphate]]
[[Category: Nucleoside triphosphate]]
[[Category: Nucleotide binding]]
[[Category: Phosphorylation]]
[[Category: Transferase]]
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