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==Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator==
==Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator==
<StructureSection load='3pmx' size='340' side='right' caption='[[3pmx]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
<StructureSection load='3pmx' size='340' side='right'caption='[[3pmx]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3pmx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PMX FirstGlance]. <br>
<table><tr><td colspan='2'>[[3pmx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PMX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=808:N-[(2S)-5-{[5-(TRIFLUOROMETHYL)FURAN-2-YL]METHYL}-2,3-DIHYDRO-1H-INDEN-2-YL]PROPANE-2-SULFONAMIDE'>808</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.87&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o28|3o28]], [[3o29|3o29]], [[3o2a|3o2a]], [[3o6g|3o6g]], [[3o6h|3o6h]], [[3o6i|3o6i]], [[3pmv|3pmv]], [[3pmw|3pmw]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=808:N-[(2S)-5-{[5-(TRIFLUOROMETHYL)FURAN-2-YL]METHYL}-2,3-DIHYDRO-1H-INDEN-2-YL]PROPANE-2-SULFONAMIDE'>808</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Gria2, Glur2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pmx OCA], [https://pdbe.org/3pmx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pmx RCSB], [https://www.ebi.ac.uk/pdbsum/3pmx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pmx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pmx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pmx RCSB], [http://www.ebi.ac.uk/pdbsum/3pmx PDBsum]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3pmx" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Ionotropic Glutamate Receptors|Ionotropic Glutamate Receptors]]
*[[Glutamate receptor 3D structures|Glutamate receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Brown, C I]]
[[Category: Brown CI]]
[[Category: Campbell, R A]]
[[Category: Campbell RA]]
[[Category: Gillen, K J]]
[[Category: Gillen KJ]]
[[Category: Gillespie, J]]
[[Category: Gillespie J]]
[[Category: Jamieson, C]]
[[Category: Jamieson C]]
[[Category: Kazemier, B]]
[[Category: Kazemier B]]
[[Category: Kiczun, M]]
[[Category: Kiczun M]]
[[Category: Lamont, Y]]
[[Category: Lamont Y]]
[[Category: Lyons, A J]]
[[Category: Lyons AJ]]
[[Category: Maclean, J K.F]]
[[Category: Maclean JKF]]
[[Category: Moir, E M]]
[[Category: Moir EM]]
[[Category: Morrow, J A]]
[[Category: Morrow JA]]
[[Category: Pantling, J]]
[[Category: Pantling J]]
[[Category: Rankovic, Z]]
[[Category: Rankovic Z]]
[[Category: Smith, L]]
[[Category: Smith L]]
[[Category: Chimera protein]]
[[Category: Fusion protein]]
[[Category: Membrane protein]]
[[Category: Transport protein]]
Retrieved from "https://proteopedia.org/3pmx"