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==Crystal structure of pyridoxal biosynthesis lyase PdxS from Pyrococcus==
==Crystal structure of pyridoxal biosynthesis lyase PdxS from Pyrococcus==
<StructureSection load='4fir' size='340' side='right' caption='[[4fir]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
<StructureSection load='4fir' size='340' side='right'caption='[[4fir]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4fir]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii_ot3 Pyrococcus horikoshii ot3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FIR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FIR FirstGlance]. <br>
<table><tr><td colspan='2'>[[4fir]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FIR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=R5P:RIBOSE-5-PHOSPHATE'>R5P</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fiq|4fiq]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=R5P:RIBOSE-5-PHOSPHATE'>R5P</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pdxS, PH1355 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii OT3])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fir OCA], [https://pdbe.org/4fir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fir RCSB], [https://www.ebi.ac.uk/pdbsum/4fir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fir ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fir OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fir RCSB], [http://www.ebi.ac.uk/pdbsum/4fir PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PDXS_PYRHO PDXS_PYRHO] Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.[HAMAP-Rule:MF_01824]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4fir" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pyrococcus horikoshii ot3]]
[[Category: Large Structures]]
[[Category: Lee, H H]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Matsuura, A]]
[[Category: Lee HH]]
[[Category: Suh, S W]]
[[Category: Matsuura A]]
[[Category: Yoon, H J]]
[[Category: Suh SW]]
[[Category: Yoon, J Y]]
[[Category: Yoon HJ]]
[[Category: Lyase]]
[[Category: Yoon JY]]
[[Category: Pdx]]
[[Category: Pyridoxal biosynthesis lyase]]
[[Category: Pyrococcus horikoshii]]