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==Crystal structure of type effector Tse1 from Pseudomonas aeruginousa==
==Crystal structure of type effector Tse1 from Pseudomonas aeruginousa==
<StructureSection load='4f0v' size='340' side='right' caption='[[4f0v]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='4f0v' size='340' side='right'caption='[[4f0v]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4f0v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F0V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F0V FirstGlance]. <br>
<table><tr><td colspan='2'>[[4f0v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F0V FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e0w|4e0w]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f0v OCA], [https://pdbe.org/4f0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f0v RCSB], [https://www.ebi.ac.uk/pdbsum/4f0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f0v ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA1844 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 Pseudomonas aeruginosa PAO1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f0v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4f0v RCSB], [http://www.ebi.ac.uk/pdbsum/4f0v PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TSE1_PSEAE TSE1_PSEAE] Toxin secreted by the H1 type VI (H1-T6SS) secretion system into the periplasm of recipient cells. Degrades peptidoglycan via amidase activity thereby helping itself to compete with other bacteria (PubMed:21776080, PubMed:22931054, PubMed:22813741, PubMed:22700987). To protect itself, the bacterium synthesizes immunity protein Tsi1 that specifically interacts with and inactivates cognate toxin (PubMed:21776080, PubMed:22931054, PubMed:22700987).<ref>PMID:21776080</ref> <ref>PMID:22700987</ref> <ref>PMID:22813741</ref> <ref>PMID:22931054</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4f0v" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pseudomonas aeruginosa pao1]]
[[Category: Large Structures]]
[[Category: Dong, Y H]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Gao, Z Q]]
[[Category: Dong YH]]
[[Category: Zhang, H]]
[[Category: Gao ZQ]]
[[Category: Hydrolase]]
[[Category: Zhang H]]
[[Category: Nlpc/p60 domain]]
[[Category: Type vi amidase effector]]

Latest revision as of 04:27, 7 October 2022

Crystal structure of type effector Tse1 from Pseudomonas aeruginousa

4f0v, resolution 1.60Å

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