4x41: Difference between revisions
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New page: '''Unreleased structure''' The entry 4x41 is ON HOLD Authors: Lee, W.C., Ho, M.C. Description: Crystal Structure of Protein Arginine Methyltransferase PRMT8 |
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==Crystal Structure of Protein Arginine Methyltransferase PRMT8== | |||
<StructureSection load='4x41' size='340' side='right'caption='[[4x41]], [[Resolution|resolution]] 3.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4x41]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X41 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X41 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x41 OCA], [https://pdbe.org/4x41 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x41 RCSB], [https://www.ebi.ac.uk/pdbsum/4x41 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x41 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ANM8_HUMAN ANM8_HUMAN] Membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA). Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS.<ref>PMID:16051612</ref> <ref>PMID:17925405</ref> <ref>PMID:18320585</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ho MC]] | |||
[[Category: Lee WC]] | |||
Latest revision as of 09:02, 20 March 2024
Crystal Structure of Protein Arginine Methyltransferase PRMT8
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