4x5m: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: '''Unreleased structure''' The entry 4x5m is ON HOLD Authors: Lee, Y, Nishizawa, T, Yamashita, K, Ishitani, R, Nureki, O Description: |
No edit summary |
||
| (9 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of SemiSWEET in the inward-open conformation== | |||
<StructureSection load='4x5m' size='340' side='right'caption='[[4x5m]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4x5m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_UMEA_3162-1 Escherichia coli UMEA 3162-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X5M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X5M FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x5m OCA], [https://pdbe.org/4x5m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x5m RCSB], [https://www.ebi.ac.uk/pdbsum/4x5m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x5m ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SWEET_ECOU3 SWEET_ECOU3] The homodimer mediates transmembrane sugar transport down a concentration gradient. Transport is probably effected by rocking-type movements, where a cargo-binding cavity opens first on one and then on the other side of the membrane.<ref>PMID:25598322</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli UMEA 3162-1]] | |||
[[Category: Large Structures]] | |||
[[Category: Ishitani R]] | |||
[[Category: Lee Y]] | |||
[[Category: Nishizawa T]] | |||
[[Category: Nureki O]] | |||
[[Category: Yamashita K]] | |||