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[[Image:1oj1.jpg|left|200px]]


{{Structure
==Nonproductive and Novel Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two Crystal Structures Complexed with (2,5 CpG) and d(ApCpGpA)==
|PDB= 1oj1 |SIZE=350|CAPTION= <scene name='initialview01'>1oj1</scene>, resolution 2.1&Aring;
<StructureSection load='1oj1' size='340' side='right'caption='[[1oj1]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+A'>AC1</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=CG2:CYTIDYL-2'-5'-PHOSPHO-GUANOSINE'>CG2</scene>
<table><tr><td colspan='2'>[[1oj1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_catesbeianus Lithobates catesbeianus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OJ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OJ1 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CG2:CYTIDYL-2-5-PHOSPHO-GUANOSINE'>CG2</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oj1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oj1 OCA], [https://pdbe.org/1oj1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oj1 RCSB], [https://www.ebi.ac.uk/pdbsum/1oj1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oj1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9DFY5_LITCT Q9DFY5_LITCT]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oj/1oj1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oj1 ConSurf].
<div style="clear:both"></div>


'''NONPRODUCTIVE AND NOVEL BINDING MODES IN CYTOTOXIC RIBONUCLEASES FROM RANA CATESBEIANA OF TWO CRYSTAL STRUCTURES COMPLEXED WITH (2,5 CPG) AND D(APCPGPA)'''
==See Also==
 
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1OJ1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rana_catesbeiana Rana catesbeiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OJ1 OCA].
[[Category: Large Structures]]
[[Category: Rana catesbeiana]]
[[Category: Lithobates catesbeianus]]
[[Category: Single protein]]
[[Category: Chen L-y]]
[[Category: Chen, L Y.]]
[[Category: Cheng P-T]]
[[Category: Cheng, P T.]]
[[Category: Liao Y-D]]
[[Category: Liao, Y D.]]
[[Category: Liu J-H]]
[[Category: Liu, J H.]]
[[Category: Sun Y-J]]
[[Category: Sun, Y J.]]
[[Category: Tsai C-J]]
[[Category: Tsai, C J.]]
[[Category: CG2]]
[[Category: SO4]]
[[Category: anti-tumor activity]]
[[Category: cytotoxic ribonuclease]]
[[Category: hydrolase]]
[[Category: sialic binding and nucleotide binding]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:11:35 2008''
Retrieved from "https://proteopedia.org/1oj1"