4i9n: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Crystal structure of rabbit LDHA in complex with AP28161 and AP28122==
==Crystal structure of rabbit LDHA in complex with AP28161 and AP28122==
<StructureSection load='4i9n' size='340' side='right' caption='[[4i9n]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='4i9n' size='340' side='right'caption='[[4i9n]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4i9n]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I9N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I9N FirstGlance]. <br>
<table><tr><td colspan='2'>[[4i9n]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I9N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I9N FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1E5:6-[3-(CARBOXYMETHOXY)-5-FLUOROPHENYL]PYRIDINE-3-CARBOXYLIC+ACID'>1E5</scene>, <scene name='pdbligand=1E6:6-({2-[(5-CHLORO-4-{[(2S)-2,3-DIHYDROXYPROPYL]OXY}-2-METHOXYPHENYL)AMINO]-2-OXOETHYL}SULFANYL)PYRIDINE-3-CARBOXYLIC+ACID'>1E6</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4i8x|4i8x]], [[4i9h|4i9h]], [[4i9u|4i9u]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1E5:6-[3-(CARBOXYMETHOXY)-5-FLUOROPHENYL]PYRIDINE-3-CARBOXYLIC+ACID'>1E5</scene>, <scene name='pdbligand=1E6:6-({2-[(5-CHLORO-4-{[(2S)-2,3-DIHYDROXYPROPYL]OXY}-2-METHOXYPHENYL)AMINO]-2-OXOETHYL}SULFANYL)PYRIDINE-3-CARBOXYLIC+ACID'>1E6</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i9n OCA], [https://pdbe.org/4i9n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i9n RCSB], [https://www.ebi.ac.uk/pdbsum/4i9n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i9n ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i9n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i9n RCSB], [http://www.ebi.ac.uk/pdbsum/4i9n PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LDHA_RABIT LDHA_RABIT]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 16: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4i9n" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: L-lactate dehydrogenase]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Commodore, L]]
[[Category: Commodore L]]
[[Category: Dalgarno, D C]]
[[Category: Dalgarno DC]]
[[Category: Greenfield, M T]]
[[Category: Greenfield MT]]
[[Category: Kohlmann, A]]
[[Category: Kohlmann A]]
[[Category: Li, F]]
[[Category: Li F]]
[[Category: Shakespeare, W C]]
[[Category: Shakespeare WC]]
[[Category: Stephan, Z G]]
[[Category: Stephan ZG]]
[[Category: Zhou, T]]
[[Category: Zhou T]]
[[Category: Zhu, X]]
[[Category: Zhu X]]
[[Category: Cancer]]
[[Category: Fragment]]
[[Category: Inhibitor]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
Retrieved from "https://proteopedia.org/4i9n"