4x7z: Difference between revisions

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New page: '''Unreleased structure''' The entry 4x7z is ON HOLD Authors: Bernard, S.M., Smith, J.L. Description:
 
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'''Unreleased structure'''


The entry 4x7z is ON HOLD
==MycF mycinamicin III 3'-O-methyltransferase (E35Q, M56A, E139A variant) in complex with Mg, SAH and mycinamicin III (substrate)==
 
<StructureSection load='4x7z' size='340' side='right'caption='[[4x7z]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
Authors: Bernard, S.M., Smith, J.L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4x7z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Micromonospora_griseorubida Micromonospora griseorubida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X7Z FirstGlance]. <br>
Description:
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.44&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZM3:MYCINAMICIN+III'>ZM3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x7z OCA], [https://pdbe.org/4x7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x7z RCSB], [https://www.ebi.ac.uk/pdbsum/4x7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x7z ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MYCF_MICGR MYCF_MICGR] O-methyltransferase that catalyzes the conversion of mycinamicin III to mycinamicin IV in the biosynthesis of mycinamicin, a 16-membered macrolide antibiotic.<ref>PMID:19415708</ref> <ref>PMID:7808395</ref> <ref>PMID:8163162</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Micromonospora griseorubida]]
[[Category: Bernard SM]]
[[Category: Smith JL]]