1p5k: Difference between revisions

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[[Image:1p5k.gif|left|200px]]


{{Structure
==HP (2-20) Substitution SER to LEU11 modification in sds-d25 micelles==
|PDB= 1p5k |SIZE=350|CAPTION= <scene name='initialview01'>1p5k</scene>
<StructureSection load='1p5k' size='340' side='right'caption='[[1p5k]]' scene=''>
|SITE=
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
<table><tr><td colspan='2'>[[1p5k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_J99 Helicobacter pylori J99]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P5K FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p5k OCA], [https://pdbe.org/1p5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p5k RCSB], [https://www.ebi.ac.uk/pdbsum/1p5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p5k ProSAT]</span></td></tr>
 
</table>
'''HP (2-20) Substitution SER to LEU11 modification in sds-d25 micelles'''
== Function ==
 
[https://www.uniprot.org/uniprot/RL1_HELPY RL1_HELPY] Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity).[HAMAP-Rule:MF_01318]  Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA (By similarity).[HAMAP-Rule:MF_01318] Peptides originating from the N-terminal end of L1 have antibacterial activity against bacteria such as E.coli and B.megaterium and modest antifungal activities. Has no effect on H.pylori itself. Peptides are not hemolytic against mammalian cells. These peptides may be released in the stomach during altruistic lysis to kill other fast growing bacteria.[HAMAP-Rule:MF_01318]
 
__TOC__
==About this Structure==
</StructureSection>
1P5K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P5K OCA].  
[[Category: Helicobacter pylori J99]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Harm, K S.]]
[[Category: Harm KS]]
[[Category: Kim, Y M.]]
[[Category: Kim YM]]
[[Category: Lee, D G.]]
[[Category: Lee DG]]
[[Category: Lee, K H.]]
[[Category: Lee KH]]
[[Category: Park, Y K.]]
[[Category: Park YK]]
[[Category: NH2]]
[[Category: coil-helix-coil]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:20:09 2008''
Retrieved from "https://proteopedia.org/1p5k"