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==Crystal structure of the P60 Domain from M. avium subspecies paratuberculosis antigen MAP1204==
==Crystal structure of the P60 Domain from M. avium subspecies paratuberculosis antigen MAP1204==
<StructureSection load='3i86' size='340' side='right' caption='[[3i86]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3i86' size='340' side='right'caption='[[3i86]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3i86]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_avium_subsp._paratuberculosis Mycobacterium avium subsp. paratuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I86 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I86 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3i86]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_avium_subsp._paratuberculosis Mycobacterium avium subsp. paratuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I86 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gt2|3gt2]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAP1204, MAP_1204 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1770 Mycobacterium avium subsp. paratuberculosis])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i86 OCA], [https://pdbe.org/3i86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i86 RCSB], [https://www.ebi.ac.uk/pdbsum/3i86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i86 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-D-glutamyl-meso-diaminopimelate_peptidase Gamma-D-glutamyl-meso-diaminopimelate peptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.11 3.4.19.11] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i86 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i86 RCSB], [http://www.ebi.ac.uk/pdbsum/3i86 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q740Y8_MYCPA Q740Y8_MYCPA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i8/3i86_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i8/3i86_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i86 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Gamma-D-glutamyl-meso-diaminopimelate peptidase]]
[[Category: Large Structures]]
[[Category: Mycobacterium avium subsp. paratuberculosis]]
[[Category: Mycobacterium avium subsp. paratuberculosis]]
[[Category: Bannantine, J P]]
[[Category: Bannantine JP]]
[[Category: Bouyain, S]]
[[Category: Bouyain S]]
[[Category: Geisbrecht, B V]]
[[Category: Geisbrecht BV]]
[[Category: Lingle, C K]]
[[Category: Lingle CK]]
[[Category: McWhorter, W J]]
[[Category: McWhorter WJ]]
[[Category: Ramyar, K X]]
[[Category: Ramyar KX]]
[[Category: Alpha and beta protein]]
[[Category: Hydrolase]]
[[Category: Hypothetical cysteine protease]]

Latest revision as of 07:40, 6 September 2023

Crystal structure of the P60 Domain from M. avium subspecies paratuberculosis antigen MAP1204

3i86, resolution 2.40Å

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