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==Crystal structure of AqpZ H174G,T183F==
==Crystal structure of AqpZ H174G,T183F==
<StructureSection load='3nka' size='340' side='right' caption='[[3nka]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3nka' size='340' side='right'caption='[[3nka]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3nka]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NKA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NKA FirstGlance]. <br>
<table><tr><td colspan='2'>[[3nka]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NKA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NKA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rc2|1rc2]], [[3nk5|3nk5]], [[3nkc|3nkc]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aqpZ, b0875, bniP, JW0859 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nka OCA], [https://pdbe.org/3nka PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nka RCSB], [https://www.ebi.ac.uk/pdbsum/3nka PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nka ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nka OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nka RCSB], [http://www.ebi.ac.uk/pdbsum/3nka PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AQPZ_ECOLI AQPZ_ECOLI] Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.<ref>PMID:10400575</ref> <ref>PMID:10518952</ref> <ref>PMID:11493683</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3nka" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Aquaporin|Aquaporin]]
*[[Aquaporin 3D structures|Aquaporin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli K-12]]
[[Category: Finer-Moore, J]]
[[Category: Large Structures]]
[[Category: III, J D.O Connell]]
[[Category: Finer-Moore J]]
[[Category: Savage, D F]]
[[Category: O'Connell III JD]]
[[Category: Stroud, R M]]
[[Category: Savage DF]]
[[Category: Aquaporin]]
[[Category: Stroud RM]]
[[Category: Integral membrane protein]]
[[Category: Selectivity filter mutant]]
[[Category: Transport protein]]