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[[Image:1pqw.gif|left|200px]]


{{Structure
==Putative enoyl reductase domain of polyketide synthase==
|PDB= 1pqw |SIZE=350|CAPTION= <scene name='initialview01'>1pqw</scene>, resolution 2.66&Aring;
<StructureSection load='1pqw' size='340' side='right'caption='[[1pqw]], [[Resolution|resolution]] 2.66&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
<table><tr><td colspan='2'>[[1pqw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_CDC1551 Mycobacterium tuberculosis CDC1551]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PQW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PQW FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.66&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pqw OCA], [https://pdbe.org/1pqw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pqw RCSB], [https://www.ebi.ac.uk/pdbsum/1pqw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pqw ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1pqw TOPSAN]</span></td></tr>
 
</table>
'''Putative enoyl reductase domain of polyketide synthase'''
== Function ==
 
[https://www.uniprot.org/uniprot/PPSC_MYCTU PPSC_MYCTU] Involved in the elongation of either C22-24 fatty acids by the addition of malonyl-CoA and methylmalonyl-CoA extender units to yield phthiocerol derivatives.
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
1PQW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_cdc1551 Mycobacterium tuberculosis cdc1551]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PQW OCA].  
Check<jmol>
[[Category: Mycobacterium tuberculosis cdc1551]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pq/1pqw_consurf.spt"</scriptWhenChecked>
[[Category: Burley, S K.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Gogos, A.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Mu, H.]]
  </jmolCheckbox>
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pqw ConSurf].
[[Category: Shapiro, L.]]
<div style="clear:both"></div>
[[Category: CA]]
__TOC__
[[Category: dimer]]
</StructureSection>
[[Category: new york structural genomix research consortium]]
[[Category: Large Structures]]
[[Category: nysgxrc]]
[[Category: Mycobacterium tuberculosis CDC1551]]
[[Category: protein structure initiative]]
[[Category: Burley SK]]
[[Category: psi]]
[[Category: Gogos A]]
[[Category: rossmann fold]]
[[Category: Mu H]]
[[Category: structural genomic]]
[[Category: Shapiro L]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:27:50 2008''

Latest revision as of 08:10, 14 February 2024

Putative enoyl reductase domain of polyketide synthase

1pqw, resolution 2.66Å

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