1psw: Difference between revisions
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==Structure of E. coli ADP-heptose lps heptosyltransferase II== | |||
<StructureSection load='1psw' size='340' side='right'caption='[[1psw]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
| | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1psw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PSW FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1psw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1psw OCA], [https://pdbe.org/1psw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1psw RCSB], [https://www.ebi.ac.uk/pdbsum/1psw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1psw ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1psw TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/WAAF_ECOLI WAAF_ECOLI] Glycosyltransferase involved in the biosynthesis of the core oligosaccharide region of lipopolysaccharide (LPS) (PubMed:11054112). Catalyzes the addition of the second heptose unit to the heptosyl-Kdo2-lipid A module (PubMed:11054112, PubMed:11717579). The analog ADP-mannose can serve as an alternative donor in place of ADP-L-glycero-D-manno-heptose, but with lower efficiency (PubMed:11054112).<ref>PMID:11054112</ref> <ref>PMID:11717579</ref> | |||
== Evolutionary Conservation == | |||
== | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/1psw_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1psw ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Buglino | [[Category: Buglino J]] | ||
[[Category: Burley | [[Category: Burley SK]] | ||
[[Category: Kniewel | [[Category: Kniewel R]] | ||
[[Category: Lima | [[Category: Lima CD]] | ||
[[Category: Solorzano V]] | |||
[[Category: Solorzano | [[Category: Wu J]] | ||
[[Category: Wu | |||
Latest revision as of 07:13, 30 October 2024
Structure of E. coli ADP-heptose lps heptosyltransferase II
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