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==Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway==
==Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway==
<StructureSection load='2xft' size='340' side='right' caption='[[2xft]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='2xft' size='340' side='right'caption='[[2xft]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xft]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XFT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xft]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XFT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xep|2xep]], [[2xf3|2xf3]], [[2xfs|2xfs]], [[2xgn|2xgn]], [[2xh9|2xh9]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xft OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xft RCSB], [http://www.ebi.ac.uk/pdbsum/2xft PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xft OCA], [https://pdbe.org/2xft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xft RCSB], [https://www.ebi.ac.uk/pdbsum/2xft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xft ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8KRB7_STRCL Q8KRB7_STRCL]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2xft" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptomyces clavuligerus]]
[[Category: Streptomyces clavuligerus]]
[[Category: Andersson, I]]
[[Category: Andersson I]]
[[Category: Dubus, A]]
[[Category: Dubus A]]
[[Category: Genereux, C]]
[[Category: Genereux C]]
[[Category: Iqbal, A]]
[[Category: Iqbal A]]
[[Category: Ivison, D]]
[[Category: Ivison D]]
[[Category: Kershaw, N J]]
[[Category: Kershaw NJ]]
[[Category: Schofield, C J]]
[[Category: Schofield CJ]]
[[Category: Valegard, K]]
[[Category: Valegard K]]
[[Category: Hydrolase]]

Latest revision as of 10:38, 16 August 2023

Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway

2xft, resolution 1.80Å

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