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==CRYSTAL STRUCTURE OF THE HUMAN DERIVED SINGLE CHAIN ANTIBODY FRAGMENT (SCFV) 9004G IN COMPLEX WITH CN2 TOXIN FROM THE SCORPION CENTRUROIDES NOXIUS HOFFMANN==
 
<StructureSection load='2ybr' size='340' side='right' caption='[[2ybr]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
==Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann==
<StructureSection load='2ybr' size='340' side='right'caption='[[2ybr]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ybr]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Centruroides_noxius Centruroides noxius] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YBR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YBR FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ybr]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Centruroides_noxius Centruroides noxius] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YBR FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1cn2|1cn2]], [[2yc1|2yc1]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ybr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ybr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ybr RCSB], [http://www.ebi.ac.uk/pdbsum/2ybr PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ybr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ybr OCA], [https://pdbe.org/2ybr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ybr RCSB], [https://www.ebi.ac.uk/pdbsum/2ybr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ybr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SCX2_CENNO SCX2_CENNO] Mammal beta-toxins bind voltage-independently at site-4 of sodium channels and shift the activation voltage to more negative potentials. This toxin is active against mammals.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2ybr" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Monoclonal Antibody|Monoclonal Antibody]]
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
*[[3D structures of human antibody|3D structures of human antibody]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Centruroides noxius]]
[[Category: Centruroides noxius]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Becerril, B]]
[[Category: Large Structures]]
[[Category: Canul-Tec, J C]]
[[Category: Becerril B]]
[[Category: Possani, L D]]
[[Category: Canul-Tec JC]]
[[Category: Riano-Umbarila, L]]
[[Category: Possani LD]]
[[Category: Rudino-Pinera, E]]
[[Category: Riano-Umbarila L]]
[[Category: Torres-Larios, A]]
[[Category: Rudino-Pinera E]]
[[Category: Immune system-toxin complex]]
[[Category: Torres-Larios A]]
[[Category: Scorpion toxin]]
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