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==THERMOSTABILISED HUMAN A2A RECEPTOR WITH ADENOSINE BOUND==
 
<StructureSection load='2ydo' size='340' side='right' caption='[[2ydo]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
==Thermostabilised HUMAN A2a Receptor with adenosine bound==
<StructureSection load='2ydo' size='340' side='right'caption='[[2ydo]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ydo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YDO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YDO FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ydo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YDO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YDO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=SOG:2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL'>SOG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1upe|1upe]], [[1mmh|1mmh]], [[2ydv|2ydv]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=SOG:2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL'>SOG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ydo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ydo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ydo RCSB], [http://www.ebi.ac.uk/pdbsum/2ydo PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ydo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ydo OCA], [https://pdbe.org/2ydo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ydo RCSB], [https://www.ebi.ac.uk/pdbsum/2ydo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ydo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2ydo" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Adenosine A2A receptor|Adenosine A2A receptor]]
*[[Adenosine A2A receptor|Adenosine A2A receptor]]
*[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bennett, K]]
[[Category: Large Structures]]
[[Category: Edwards, P C]]
[[Category: Bennett K]]
[[Category: Langmead, C J]]
[[Category: Edwards PC]]
[[Category: Lebon, G]]
[[Category: Langmead CJ]]
[[Category: Leslie, A G.W]]
[[Category: Lebon G]]
[[Category: Tate, C G]]
[[Category: Leslie AGW]]
[[Category: Warne, T]]
[[Category: Tate CG]]
[[Category: 7tm receptor]]
[[Category: Warne T]]
[[Category: Agonist bound form]]
[[Category: G protein coupled receptor]]
[[Category: Gpcr]]
[[Category: Receptor]]
[[Category: Seven-helix receptor]]
[[Category: Thermostabilising point mutation]]
Retrieved from "https://proteopedia.org/2ydo"