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==The crystal structure of human Glia Maturation Factor, Gamma (GMFG)==
==The crystal structure of human Glia Maturation Factor, Gamma (GMFG)==
<StructureSection load='3l50' size='340' side='right' caption='[[3l50]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3l50' size='340' side='right'caption='[[3l50]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3l50]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L50 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L50 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3l50]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L50 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L50 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vkk|1vkk]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GMFG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l50 OCA], [https://pdbe.org/3l50 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l50 RCSB], [https://www.ebi.ac.uk/pdbsum/3l50 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l50 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l50 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l50 RCSB], [http://www.ebi.ac.uk/pdbsum/3l50 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GMFG_HUMAN GMFG_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l5/3l50_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l5/3l50_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l50 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H]]
[[Category: Large Structures]]
[[Category: Bountra, C]]
[[Category: Arrowsmith CH]]
[[Category: Delft, F von]]
[[Category: Bountra C]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Hapka, E]]
[[Category: Hapka E]]
[[Category: Kavanagh, K L]]
[[Category: Kavanagh KL]]
[[Category: Krojer, T]]
[[Category: Krojer T]]
[[Category: Krysztofinska, E]]
[[Category: Krysztofinska E]]
[[Category: Muniz, J]]
[[Category: Muniz J]]
[[Category: Oppermann, U]]
[[Category: Oppermann U]]
[[Category: Pike, A C.W]]
[[Category: Pike ACW]]
[[Category: Pilka, E]]
[[Category: Pilka E]]
[[Category: Structural genomic]]
[[Category: Ugochukwu E]]
[[Category: Ugochukwu, E]]
[[Category: Vollmar M]]
[[Category: Vollmar, M]]
[[Category: Weigelt J]]
[[Category: Weigelt, J]]
[[Category: Von Delft F]]
[[Category: Gamma]]
[[Category: Glia maturation factor]]
[[Category: Gmfg]]
[[Category: Growth factor]]
[[Category: Hormone]]
[[Category: Human]]
[[Category: Sgc]]

Latest revision as of 16:20, 1 November 2023

The crystal structure of human Glia Maturation Factor, Gamma (GMFG)

3l50, resolution 1.90Å

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