3ju6: Difference between revisions

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==Crystal Structure of Dimeric Arginine Kinase in Complex with AMPPNP and Arginine==
==Crystal Structure of Dimeric Arginine Kinase in Complex with AMPPNP and Arginine==
<StructureSection load='3ju6' size='340' side='right' caption='[[3ju6]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
<StructureSection load='3ju6' size='340' side='right'caption='[[3ju6]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ju6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Apostichopus_japonicus Apostichopus japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JU6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ju6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Apostichopus_japonicus Apostichopus japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JU6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=ARG:ARGININE'>ARG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ju5|3ju5]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ju6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju6 OCA], [https://pdbe.org/3ju6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ju6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ju6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ju6 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=307972 Apostichopus japonicus])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginine_kinase Arginine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.3 2.7.3.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ju6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ju6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ju6 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KARG_STIJA KARG_STIJA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/3ju6_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/3ju6_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ju6 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3ju6" style="background-color:#fffaf0;"></div>
==See Also==
*[[Arginine kinase 3D structures|Arginine kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Apostichopus japonicus]]
[[Category: Apostichopus japonicus]]
[[Category: Arginine kinase]]
[[Category: Large Structures]]
[[Category: Bartlam, M]]
[[Category: Bartlam M]]
[[Category: Guo, S]]
[[Category: Guo S]]
[[Category: Rao, Z]]
[[Category: Rao Z]]
[[Category: Wu, X]]
[[Category: Wu X]]
[[Category: Yan, W]]
[[Category: Yan W]]
[[Category: Ye, S]]
[[Category: Ye S]]
[[Category: Atp-binding]]
[[Category: Kinase]]
[[Category: Negative cooperativity]]
[[Category: Nucleotide-binding]]
[[Category: Phosphagen kinase]]
[[Category: Reciprocating mechanism]]
[[Category: Ternary complex]]
[[Category: Transferase]]