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==Alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain==
==Alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain==
<StructureSection load='3oj8' size='340' side='right' caption='[[3oj8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3oj8' size='340' side='right'caption='[[3oj8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3oj8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OJ8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3oj8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OJ8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=OJ8:(S)-[(2S)-6-PHENOXY-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL](5-PYRIDIN-2-YL-1,3-OXAZOL-2-YL)METHANOL'>OJ8</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wj1|2wj1]], [[2wj2|2wj2]], [[2vya|2vya]], [[3lj6|3lj6]], [[2wap|2wap]], [[3k7f|3k7f]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=OJ8:(S)-[(2S)-6-PHENOXY-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL](5-PYRIDIN-2-YL-1,3-OXAZOL-2-YL)METHANOL'>OJ8</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Faah, faah-1, Faah1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oj8 OCA], [https://pdbe.org/3oj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oj8 RCSB], [https://www.ebi.ac.uk/pdbsum/3oj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oj8 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fatty_acid_amide_hydrolase Fatty acid amide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.99 3.5.1.99] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oj8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3oj8 RCSB], [http://www.ebi.ac.uk/pdbsum/3oj8 PDBsum]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3oj8" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fatty acid amide hydrolase]]
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Boger, D L]]
[[Category: Boger DL]]
[[Category: Mileni, M]]
[[Category: Mileni M]]
[[Category: Stevens, R C]]
[[Category: Stevens RC]]
[[Category: Enantiomer]]
[[Category: Faah]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Membrane]]
[[Category: Oxazole]]
[[Category: Protein-inhibitor complex]]
[[Category: Serine hydrolase]]
Retrieved from "https://proteopedia.org/3oj8"