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==The crystal structure of the W169Y mutant of alpha-glucosidase (gh31 family) from Ruminococcus obeum atcc 29174 in complex with acarbose==
==The crystal structure of the W169Y mutant of alpha-glucosidase (gh31 family) from Ruminococcus obeum atcc 29174 in complex with acarbose==
<StructureSection load='3pha' size='340' side='right' caption='[[3pha]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
<StructureSection load='3pha' size='340' side='right'caption='[[3pha]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3pha]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ruminococcus_obeum_atcc_29174 Ruminococcus obeum atcc 29174]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3nxm 3nxm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PHA FirstGlance]. <br>
<table><tr><td colspan='2'>[[3pha]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Blautia_obeum_ATCC_29174 Blautia obeum ATCC 29174]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3nxm 3nxm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PHA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACR:ALPHA-ACARBOSE'>ACR</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.173&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nxm|3nxm]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AC1:6-METHYL-5-(4,5,6-TRIHYDROXY-3-HYDROXYMETHYL-CYCLOHEX-2-ENYLAMINO)-TETRAHYDRO-PYRAN-2,3,4-TRIOL'>AC1</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900007:alpha-acarbose'>PRD_900007</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RUMOBE_03919 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=411459 Ruminococcus obeum ATCC 29174])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pha OCA], [https://pdbe.org/3pha PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pha RCSB], [https://www.ebi.ac.uk/pdbsum/3pha PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pha ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pha OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pha RCSB], [http://www.ebi.ac.uk/pdbsum/3pha PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A5ZY13_9FIRM A5ZY13_9FIRM]
==See Also==
*[[Alpha-glucosidase 3D structures|Alpha-glucosidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ruminococcus obeum atcc 29174]]
[[Category: Blautia obeum ATCC 29174]]
[[Category: Babnigg, G]]
[[Category: Large Structures]]
[[Category: Joachimiak, A]]
[[Category: Babnigg G]]
[[Category: Keigher, L]]
[[Category: Joachimiak A]]
[[Category: Structural genomic]]
[[Category: Keigher L]]
[[Category: Tan, K]]
[[Category: Tan K]]
[[Category: Tesar, C]]
[[Category: Tesar C]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Mcsg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Structuralcomplex]]

Latest revision as of 09:54, 6 September 2023

The crystal structure of the W169Y mutant of alpha-glucosidase (gh31 family) from Ruminococcus obeum atcc 29174 in complex with acarbose

3pha, resolution 2.17Å

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