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==The crystal structure of alanine racemase from streptococcus pneumoniae==
==The crystal structure of alanine racemase from streptococcus pneumoniae==
<StructureSection load='3s46' size='340' side='right' caption='[[3s46]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3s46' size='340' side='right'caption='[[3s46]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3s46]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3mub 3mub]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S46 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S46 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3s46]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3mub 3mub]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S46 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S46 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=LLP:2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE)'>LLP</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">alaR, alr, SP_1698 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 Streptococcus pneumoniae])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s46 OCA], [https://pdbe.org/3s46 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s46 RCSB], [https://www.ebi.ac.uk/pdbsum/3s46 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s46 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine_racemase Alanine racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.1 5.1.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s46 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3s46 RCSB], [http://www.ebi.ac.uk/pdbsum/3s46 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ALR_STRPN ALR_STRPN] Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3s46" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Alanine racemase|Alanine racemase]]
*[[Alanine racemase 3D structures|Alanine racemase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alanine racemase]]
[[Category: Large Structures]]
[[Category: Streptococcus pneumoniae]]
[[Category: Streptococcus pneumoniae]]
[[Category: Davlieva, M]]
[[Category: Davlieva M]]
[[Category: Im, H]]
[[Category: Im H]]
[[Category: Krause, K L]]
[[Category: Krause KL]]
[[Category: Sharpe, M L]]
[[Category: Sharpe ML]]
[[Category: Strych, U]]
[[Category: Strych U]]
[[Category: Alpha/beta barrel]]
[[Category: Carbamylated lysine]]
[[Category: Extended beta-strand domain]]
[[Category: Isomerase]]
[[Category: Pyridoxal phosphate cofactor]]