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==Tetrameric form of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO)==
==Tetrameric form of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO)==
<StructureSection load='4h2p' size='340' side='right' caption='[[4h2p]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
<StructureSection load='4h2p' size='340' side='right'caption='[[4h2p]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4h2p]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesorhizobium_loti_maff303099 Mesorhizobium loti maff303099]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H2P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H2P FirstGlance]. <br>
<table><tr><td colspan='2'>[[4h2p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesorhizobium_japonicum_MAFF_303099 Mesorhizobium japonicum MAFF 303099]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H2P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H2P FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.981&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3alh|3alh]], [[3ali|3ali]], [[3alk|3alk]], [[4h28|4h28]], [[4h2n|4h2n]], [[4h2q|4h2q]], [[4h2r|4h2r]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mlr6788 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=266835 Mesorhizobium loti MAFF303099])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h2p OCA], [https://pdbe.org/4h2p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h2p RCSB], [https://www.ebi.ac.uk/pdbsum/4h2p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h2p ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxy-2-methylpyridinecarboxylate_dioxygenase 3-hydroxy-2-methylpyridinecarboxylate dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.4 1.14.12.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h2p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h2p RCSB], [http://www.ebi.ac.uk/pdbsum/4h2p PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q988D3_RHILO Q988D3_RHILO]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 3-hydroxy-2-methylpyridinecarboxylate dioxygenase]]
[[Category: Large Structures]]
[[Category: Mesorhizobium loti maff303099]]
[[Category: Mesorhizobium japonicum MAFF 303099]]
[[Category: Hayashi, H]]
[[Category: Hayashi H]]
[[Category: Kamitori, S]]
[[Category: Kamitori S]]
[[Category: Kobayashi, J]]
[[Category: Kobayashi J]]
[[Category: Mikami, B]]
[[Category: Mikami B]]
[[Category: Yagi, T]]
[[Category: Yagi T]]
[[Category: Yoshida, H]]
[[Category: Yoshida H]]
[[Category: 3-hydroxypyridine-5-carboxylic acid]]
[[Category: Fad]]
[[Category: Fad-binding motif]]
[[Category: Oxidoreductase]]
[[Category: Oxygenase]]

Latest revision as of 14:03, 8 November 2023

Tetrameric form of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO)

4h2p, resolution 1.98Å

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