1s9b: Difference between revisions

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[[Image:1s9b.gif|left|200px]]


{{Structure
==Crystal Structure Analysis of the B-DNA GAATTCG==
|PDB= 1s9b |SIZE=350|CAPTION= <scene name='initialview01'>1s9b</scene>, resolution 2.81&Aring;
<StructureSection load='1s9b' size='340' side='right'caption='[[1s9b]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NI:NICKEL (II) ION'>NI</scene>
<table><tr><td colspan='2'>[[1s9b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S9B FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s9b OCA], [https://pdbe.org/1s9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s9b RCSB], [https://www.ebi.ac.uk/pdbsum/1s9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s9b ProSAT]</span></td></tr>
 
</table>
'''Crystal Structure Analysis of the B-DNA GAATTCG'''
__TOC__
 
</StructureSection>
 
[[Category: Large Structures]]
==Overview==
[[Category: Gouyette C]]
DNA oligonucleotides can be used in order to assemble highly structured materials. Oligonucleotides with sticky ends can form long linear structures, whereas branching is required to form two- and three-dimensional nanostructures. In this paper, we show that when Ni(2+) is attached to the N7 atom of guanine, it can also act as a branching point. Thus, we have found that the heptanucleotide d(GAATTCG) can assemble into long linear duplex structures, which cross in space to generate a cubic structure. The three-dimensional arrays are stabilized by phosphate-Ni(2+)-guanine interactions. For the first time, the crystallization of a B form DNA oligonucleotide in a cubic system is reported, space group I23. Large solvent cavities are found among the DNA duplexes.
[[Category: Subirana JA]]
 
[[Category: Uson I]]
==About this Structure==
[[Category: Valls N]]
1S9B is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S9B OCA].  
 
==Reference==
A cubic arrangement of DNA double helices based on nickel-guanine interactions., Valls N, Uson I, Gouyette C, Subirana JA, J Am Chem Soc. 2004 Jun 30;126(25):7812-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15212528 15212528]
[[Category: Protein complex]]
[[Category: Gouyette, C.]]
[[Category: Subirana, J A.]]
[[Category: Uson, I.]]
[[Category: Valls, N.]]
[[Category: NI]]
[[Category: cubic dna]]
[[Category: double helix]]
[[Category: nickel]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:02:01 2008''

Latest revision as of 08:29, 14 February 2024

Crystal Structure Analysis of the B-DNA GAATTCG

1s9b, resolution 2.81Å

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