4l9r: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Crystal Structure of apo A12K/D35S mutant myo-inositol dehydrogenase from Bacillus subtilis==
==Crystal Structure of apo A12K/D35S mutant myo-inositol dehydrogenase from Bacillus subtilis==
<StructureSection load='4l9r' size='340' side='right' caption='[[4l9r]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='4l9r' size='340' side='right'caption='[[4l9r]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4l9r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L9R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L9R FirstGlance]. <br>
<table><tr><td colspan='2'>[[4l9r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L9R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L9R FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4l8v|4l8v]], [[3mz0|3mz0]], [[3nt2|3nt2]], [[3nt4|3nt4]], [[3nt5|3nt5]], [[3nto|3nto]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSU39700, E83G, idh, iolG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 Bacillus subtilis subsp. subtilis str. 168])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l9r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l9r OCA], [https://pdbe.org/4l9r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l9r RCSB], [https://www.ebi.ac.uk/pdbsum/4l9r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l9r ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inositol_2-dehydrogenase Inositol 2-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.18 1.1.1.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l9r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l9r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l9r RCSB], [http://www.ebi.ac.uk/pdbsum/4l9r PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IOLG_BACSU IOLG_BACSU] Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively. Can also use D-glucose and D-xylose, and shows a trace of activity with D-ribose and D-fructose.<ref>PMID:112095</ref> <ref>PMID:16461681</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 16: Line 17:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4l9r" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
Line 21: Line 23:
</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Inositol 2-dehydrogenase]]
[[Category: Large Structures]]
[[Category: Bertwistle, D]]
[[Category: Bertwistle D]]
[[Category: Palmer, D R.J]]
[[Category: Palmer DRJ]]
[[Category: Sanders, D A.R]]
[[Category: Sanders DAR]]
[[Category: Binding site]]
[[Category: Catalysis]]
[[Category: Cofactor]]
[[Category: Hydrogen bonding]]
[[Category: Inositol]]
[[Category: Kinetic]]
[[Category: Nadp binding]]
[[Category: Oxidoreductase]]
[[Category: Rossmann fold]]
[[Category: Sugar alcohol dehydrogenase]]
Retrieved from "https://proteopedia.org/4l9r"