1t3x: Difference between revisions

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[[Image:1t3x.gif|left|200px]]


{{Structure
==Three Crystal Structures of Human Coactosin-like Protein==
|PDB= 1t3x |SIZE=350|CAPTION= <scene name='initialview01'>1t3x</scene>, resolution 2.00&Aring;
<StructureSection load='1t3x' size='340' side='right'caption='[[1t3x]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1t3x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T3X FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t3x OCA], [https://pdbe.org/1t3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t3x RCSB], [https://www.ebi.ac.uk/pdbsum/1t3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t3x ProSAT]</span></td></tr>
}}
</table>
 
== Function ==
'''Three Crystal Structures of Human Coactosin-like Protein'''
[https://www.uniprot.org/uniprot/COTL1_HUMAN COTL1_HUMAN] Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization.<ref>PMID:11583571</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==Disease==
Check<jmol>
Known disease associated with this structure: Cardiomyopathy, dilated, 1M OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600824 600824]]
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t3/1t3x_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
1T3X is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3X OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t3x ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Chen, Z.]]
[[Category: Chen Z]]
[[Category: Liu, L.]]
[[Category: Liu L]]
[[Category: Wang, Y.]]
[[Category: Wang Y]]
[[Category: Wei, Z.]]
[[Category: Wei Z]]
[[Category: beta-sheet]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:13:25 2008''

Latest revision as of 13:30, 13 March 2024

Three Crystal Structures of Human Coactosin-like Protein

1t3x, resolution 2.00Å

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