1t90: Difference between revisions

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[[Image:1t90.gif|left|200px]]


{{Structure
==Crystal structure of methylmalonate semialdehyde dehydrogenase from Bacillus subtilis==
|PDB= 1t90 |SIZE=350|CAPTION= <scene name='initialview01'>1t90</scene>, resolution 2.5&Aring;
<StructureSection load='1t90' size='340' side='right'caption='[[1t90]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
<table><tr><td colspan='2'>[[1t90]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T90 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Methylmalonate-semialdehyde_dehydrogenase_(acylating) Methylmalonate-semialdehyde dehydrogenase (acylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.27 1.2.1.27]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
|GENE= MMSA, IOLA, E83A, BSU39760 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t90 OCA], [https://pdbe.org/1t90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t90 RCSB], [https://www.ebi.ac.uk/pdbsum/1t90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t90 ProSAT]</span></td></tr>
 
</table>
'''Crystal structure of methylmalonate semialdehyde dehydrogenase from Bacillus subtilis'''
== Function ==
 
[https://www.uniprot.org/uniprot/IOLA_BACSU IOLA_BACSU] Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.<ref>PMID:16332250</ref> <ref>PMID:18310071</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
1T90 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T90 OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t9/1t90_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t90 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Methylmalonate-semialdehyde dehydrogenase (acylating)]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Aubry A]]
[[Category: Aubry, A.]]
[[Category: Branlant G]]
[[Category: Branlant, G.]]
[[Category: Corbier C]]
[[Category: Corbier, C.]]
[[Category: Didierjean C]]
[[Category: Didierjean, C.]]
[[Category: Dubourg H]]
[[Category: Dubourg, H.]]
[[Category: Stines-Chaumeil C]]
[[Category: Stines-Chaumeil, C.]]
[[Category: Talfournier F]]
[[Category: Talfournier, F.]]
[[Category: NAD]]
[[Category: nad]]
[[Category: oxidoreductase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:15:27 2008''
Retrieved from "https://proteopedia.org/1t90"