1th2: Difference between revisions

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[[Image:1th2.gif|left|200px]]


{{Structure
==crystal structure of NADPH depleted bovine liver catalase complexed with azide==
|PDB= 1th2 |SIZE=350|CAPTION= <scene name='initialview01'>1th2</scene>, resolution 2.80&Aring;
<StructureSection load='1th2' size='340' side='right'caption='[[1th2]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene> and <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
<table><tr><td colspan='2'>[[1th2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TH2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TH2 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1th2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1th2 OCA], [https://pdbe.org/1th2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1th2 RCSB], [https://www.ebi.ac.uk/pdbsum/1th2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1th2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CATA_BOVIN CATA_BOVIN] Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/th/1th2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1th2 ConSurf].
<div style="clear:both"></div>


'''crystal structure of NADPH depleted bovine liver catalase complexed with azide'''
==See Also==
 
*[[Catalase 3D structures|Catalase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1TH2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TH2 OCA].
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Catalase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Balasundaresan D]]
[[Category: Balasundaresan, D.]]
[[Category: Kumaran D]]
[[Category: Kumaran, D.]]
[[Category: Ponnuswamy MN]]
[[Category: Ponnuswamy, M N.]]
[[Category: Sekar K]]
[[Category: Sekar, K.]]
[[Category: Sugadev R]]
[[Category: Sugadev, R.]]
[[Category: Swaminathan S]]
[[Category: Swaminathan, S.]]
[[Category: AZI]]
[[Category: HEM]]
[[Category: azide]]
[[Category: bovine liver catalase]]
[[Category: nadph]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:18:15 2008''