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==Solution structure of cryptdin-4, the most potent alpha-defensin from mouse Paneth cells==
==Solution structure of cryptdin-4, the most potent alpha-defensin from mouse Paneth cells==
<StructureSection load='1tv0' size='340' side='right' caption='[[1tv0]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1tv0' size='340' side='right'caption='[[1tv0]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1tv0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TV0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TV0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1tv0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TV0 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DEFCR4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tv0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tv0 RCSB], [http://www.ebi.ac.uk/pdbsum/1tv0 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tv0 OCA], [https://pdbe.org/1tv0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tv0 RCSB], [https://www.ebi.ac.uk/pdbsum/1tv0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tv0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEFA4_MOUSE DEFA4_MOUSE] Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1tv0" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Hunter, H N]]
[[Category: Hunter HN]]
[[Category: Jing, W]]
[[Category: Jing W]]
[[Category: Ouellette, A J]]
[[Category: Ouellette AJ]]
[[Category: Tanabe, H]]
[[Category: Tanabe H]]
[[Category: Vogel, H J]]
[[Category: Vogel HJ]]
[[Category: Antimicrobial protein]]
[[Category: Beta hairpin]]
[[Category: Beta sheet]]

Latest revision as of 07:29, 30 October 2024

Solution structure of cryptdin-4, the most potent alpha-defensin from mouse Paneth cells

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